Who plays Mrs. Wheeler Wheeler? What actress assumes the role of Karen Wheeler in the series? Whom is the performer behind Karen Wheeler? Karen is depicted by what actor? What actress plays the character of Karen the mother on the show? Who is the talent showcasing Karen the mother's character to life? What actor takes on the role of Karen Mrs. Wheeler in the series? Whoever takes on the part of Karen Mrs. Wheeler? Whom is the talented individual embodying Karen the mother on the show? Which actress incarnates the character of Karen Wheeler to the screen?