Who portrays Karen mother? What actor assumes the role of Karen Wheeler in the show? Who is the performer behind Karen Wheeler? Mrs. Wheeler is brought to life by whom? Who plays the character of Karen the mother on the show? Whom is the talent showcasing Karen the mother's character to life? What performer takes on the role of Karen Wheeler in the series? Whoever takes on the part of Karen Mrs. Wheeler? Who is the talented individual portraying Karen Wheeler on the series? What actress incarnates the character of Karen Wheeler to the screen?